111 Reschedules Third Quarter 2024 Unaudited Financial Results Announcement to November 27, 2024 - Conference Call to Follow

SHANGHAI,Nov. 4,2024 -- 111,Inc. ("111" or the "Company") (NASDAQ: YI),a leading tech-enabled healthcare platform company committed to reshaping the value chain of healthcare industry by digitally empowering the upstream and downstream in China,today announced that its release of unaudited financial results for the third quarter ended September 30,2024,previously scheduled for Thursday,November 28,will now occur before the U.S. market opens on Wednesday,November 27,2024.

111's management team will host an earnings conference call at7:30 AMU.S. Eastern Time onWednesday,2024(8:30 PMBeijing Time on the same day).

Details for the conference call are as follows:

Conference Topic: 111,Inc. Third Quarter 2024 Earnings Conference Call

Registration Link:https://s1.c-conf.com/diamondpass/10042738-te7sgd.html

All participants must use the link provided above to complete the online registration process in advance of the conference call. Upon registering,each participant will then be provided with the dial in number,the Passcode,and your unique access PIN. This information will also be emailed to you as a calendar invite.

Please dial in 15 minutes before the call is scheduled to begin. To join the conference,simply dial the number in the calendar invite and enter the passcode followed by your PIN,and you will join the conference instantly.

A live and archived webcast of the conference call will be available on the website athttps://edge.media-server.com/mmc/p/3nkscjv6

A telephone replay of the call will be available after the conclusion of the conference call untilDecember 4,2024.

China:

4001209216

United States:

+1-855-883-1031

International:

+61-7-3107-6325

Conference ID:

10042738

About 111,Inc.

111,Inc. (NASDAQ: YI) ("111" or the "Company") is a leading tech-enabled healthcare platform company committed to reshaping the value chain of healthcare industry by digitally empowering the upstream and downstream inChina. The Company provides consumers with better access to pharmaceutical products and healthcare services directly through its online retail pharmacy,1 Pharmacy,and indirectly through its offline virtual pharmacy network. The Company also offers online healthcare services through its internet hospital,1 Clinic,which provides consumers with cost-effective and convenient online consultation,electronic prescription service,and patient management service. In addition,the Company's online platform,1 Medicine,serves as a one-stop shop for pharmacies to source a vast selection of pharmaceutical products. With the largest virtual pharmacy network inChina,111 enables offline pharmacies to better serve their customers with cloud-based services. 111 also provides an omni-channel drug commercialization platform to its strategic partners,which includes services such as digital marketing,patient education,data analytics,and pricing monitoring.

For more information on 111,please visit:http://ir.111.com.cn/.